KmerStream: streaming algorithms for k -mer abundance estimation

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چکیده

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KmerStream: streaming algorithms for k-mer abundance estimation

MOTIVATION Several applications in bioinformatics, such as genome assemblers and error corrections methods, rely on counting and keeping track of k-mers (substrings of length k). Histograms of k-mer frequencies can give valuable insight into the underlying distribution and indicate the error rate and genome size sampled in the sequencing experiment. RESULTS We present KmerStream, a streaming ...

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Kmerlight: fast and accurate k-mer abundance estimation

k-mers (nucleotide strings of length k) form the basis of several algorithms in computational genomics. In particular, k-mer abundance information in sequence data is useful in read error correction, parameter estimation for genome assembly, digital normalization etc. We give a streaming algorithm Kmerlight for computing the k-mer abundance histogram from sequence data. Our algorithm is fast an...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2014

ISSN: 1460-2059,1367-4803

DOI: 10.1093/bioinformatics/btu713